B cell

noun

: any of the lymphocytes that have antigen-binding antibody molecules on the surface, that comprise the antibody-secreting plasma cells when mature, and that in mammals differentiate in the bone marrow : b lymphocyte
The glycoproteins produced by B cells, called antibodies or immunoglobulins, recognize and bind free antigens and are responsible for humoral immunity …Haruo Saito et al.
helper T cells that induce the proliferation of the antibody-producing B cells.N. A. Mitchison
… patients have no mature B cells circulating in the bloodstream and no antibodies to fight off infections.Jean Marx
compare t cell

Examples of B cell in a Sentence

Recent Examples on the Web
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To find those powerful antibodies, scientists sort through B cells, a type of white blood cell that makes millions of different antibodies against a particular pathogen. Tara Haelle, Scientific American, 23 Sep. 2025 Inside, lymph nodes are packed with immune cells like T cells, B cells, and dendritic cells that communicate, train, and multiply in response to threats. New Atlas, 20 Sep. 2025 It has since been joined by Mosunetuzumab, Epcoritamab, and Glofitamab, all of which mobilize T cells against malignant B cells. William A. Haseltine, Forbes.com, 18 Sep. 2025 According to the researchers, cats treated with MSC therapy had fewer overly active T and B cells (which are associated with immune overdrive) and more regulatory T cells (which can calm the immune system). Jack Knudson, Discover Magazine, 15 July 2025 See All Example Sentences for B cell

Word History

Etymology

B probably from bursa-derived (produced by the bursa of Fabricius)

First Known Use

1962, in the meaning defined above

Time Traveler
The first known use of B cell was in 1962

Browse Nearby Words

Cite this Entry

“B cell.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/B%20cell. Accessed 30 Sep. 2025.

Kids Definition

B cell

noun
ˈbē-ˌsel
: any of the lymphocytes that produce antigen-binding antibodies and that arise and mature in the bone marrow compare t cell

Medical Definition

B cell

noun
: any of the lymphocytes that have antigen-binding antibody molecules on the surface, that comprise the antibody-secreting plasma cells when mature, and that in mammals differentiate in the bone marrow

called also B lymphocyte

compare t cell

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